The Sen Lab
University of Michigan
Title (link to PDF) / Author / Publisher / Year
Peak-End Bias in Retrospective Recall of Depressive Symptoms on the PHQ-9
Adam G. Horwitz, Zhuo Zhao, and Srijan Sen
Psychological Assessment (2023). Advance online publication. https://dx.doi.org/10.1037/pas0001219
Published: February 9, 2023
Polygenic Risk and Social Support in Predicting Depression Under Stress
Jennifer L. Cleary, M.S., Yu Fang, M.S.E., Laura B. Zahodne, Ph.D., Amy S.B. Bohnert, Ph.D., Margit Burmeister, Ph.D.,
Srijan Sen, M.D., Ph.D.
The American Journal of Psychiatry (2023) https://doi-org.proxy.lib.umich.edu/10.1176/appi.ajp.21111100
Published: January 11, 2023
Effectiveness of gamified team competition as mHealth intervention for medical interns: a cluster micro-randomized trial
Jitao Wang, Yu Fang, Elena Frank, Maureen A. Walton, Margit Burmeister, Ambuj Tewari, Walter Dempsey, Timothy NeCamp, Srijan Sen, Zhenke Wu
npj Digital Medicine 6, 4 (2023). https://doi.org/10.1038/s41746-022-00746-y Published: January 11, 2023
A caveat to using wearable sensor data for COVID-19 detection: The role of behavioral change after receipt of test results
Jennifer L. Cleary, Yu Fang, Srijan Sen, Zhenke Wu
PLoS ONE 17(12): e0277350. https://doi.org/10.1371/journal. pone.0277350 Published: December 30, 2022
Is It Burnout or Depression? Expanding Efforts to Improve Physician Well-Being
Srijan Sen, M.D., Ph.D.
New England Journal of Medicine 387;18 (2022) DOI: 10.1056/NEJMp2209540 Published: November 3, 2022
Work Hours and Depression in U.S. First-Year Physicians
Yu Fang, MSE; Sara Lodi, Ph.D.; Tasha M. Hughes, M.D., M.P.H., Elena Frank, Ph.D., Srijan Sen, M.D., Ph.D., Amy S. B. Bohnert, Ph.D..
New England Journal of Medicine. (2022) doi: 10.1056/NEJMc2210365 Published: October 20, 2022
Using machine learning with intensive longitudinal data to predict depression and suicidal ideation among medical interns over time
Adam Horwitz, Shane Kentopp, Jennifer Cleary, Katherine Ross, Zhenke Wu, Srijan Sen, Ewa Czyz
Psychological Medicine. (2022) 1-8. https://doi.org/10.1017/S0033291722003014 Published: September 5, 2022
Utilizing daily mood diaries and wearable sensor data to predict depression and suicidal ideation among medical interns
Adam Horwitz, Ewa Czyz, Nadia Al-Dajani, Walter Dempsey, Zhuo Zhao, Inbal Nahum-Shani, Srijan Sen
Journal of Affective Disorders. (2022) 1-8. https://doi.org/10.1016/j.jad.2022.06.064 Published: June 25, 2022
Polygenic Liability to Depression Is Associated With Multiple Medical Conditions in the Electronic Health Record: Phenome-wide Association Study of 46,782 Individuals
Yu Fang, Lars G. Fritsche, Bhramar Mukherjee, Srijan Sen, Leah S. Richmond-Raker
Biological Psychiatry. (2022) https://doi.org/10.1016/j.biopsych.2022.06.004 Published: June 11, 2022
Prevalence and risk factors for depression among training physicians in China and the United States
Lihong Chen; Zhuo Zhao; Zhen Wang; Ying Zhou; Xin Zhou; Hui Pan; Fengtao Shen; Suhua Zeng; Xinhua Shao; Elena Frank; Srijan Sen; Weidong Li; Margit Burmeister
Scientific Reports. (2022)12:8170. doi:10.1038/s41598-022-12066-y Published: May 17, 2022
Assessment of the Prevalence and Trajectory of Depressive Symptoms by Sexual Orientation During Physician Training
Tejal H. Patel; Jennifer L. Cleary, MS; Zhuo Zhao, MS; Katherine E. T. Ross, BS; Srijan Sen, MD, PhD; Elena Frank, PhD
JAMA Health Forum. 2022;3(4):e220812. doi:10.1001/jamahealthforum.2022.0812 Published: April 29, 2022
New-Onset Depression Among Surgical Interns
Tasha M. Hughes, MD, MPH; Jennifer F. Waljee, MD, MPH; Yu Fang, MSE; Srijan Sen, MD, PhD; Amy Bohnert, PhD
JAMA Surgery. 2022 doi:10.1001/jamasurg.2022.0618 Published: April 27, 2022
Consumer-grade wearables identify changes in multiple physiological systems during COVID-19 disease progression
Caleb Mayer; Jonathan Tyler; Yu Fang; Christopher Flora; Elena Frank; Muneesh Tewari; Sung Won Choi; Srijan Sen;
Daniel B. Forger
Cell Reports Medicine. 2022;3(4):100601. https://doi.org/10.1016/j.xcrm.2022.100601 Published: April 19, 2022
Analysis of Depressive Symptoms and Perceived Impairment Among Physicians Across Intern Year
Lisa M. Meeks, PhD; Jennifer Cleary, MS; Adam Horwitz, PhD; Karina Pereira-Lima, PhD; Zhuo Zhao, MS; Yu Fang, MSE; Srijan Sen, MD, PhD
JAMA Network Open. 2022;5(1):e2144919. doi:10.1001/jamanetworkopen.2021.44919 Published: January 25, 2022
Program Access, Depressive Symptoms, and Medical Errors Among Resident Physicians With Disability
Lisa M. Meeks, PhD; Karina Pereira-Lima, PhD; Elena Frank, PhD; Erene Stergiopoulos, MD, MA; Katherine E.T. Ross, BS, BA; Srijan Sen, MD, PhD
JAMA Network Open. 2021;4(12):e2141511; doi:10.1001/jamanetworkopen.2021.41511 Published: December 30, 2021
Prediction of Suicidal Ideation Risk in a Prospective Cohort Study of Medical Interns
Tyler L. Malone, Zhou Zhao, Tzu-Ying Liu, Peter X. K. Song, Srijan Sen , Laura J. Scott
PLoS ONE 16(12): e0260620. DOI: https://doi.org/10.1371/journal.pone.0260620 Published: December 2, 2021
Trends in Depressive Symptoms and Associated Factors During Residency, 2007 to 2019
Yu Fang, MSE, Amy S.B. Bohnert, PhD, MHS, Karina Pereira-Lima, PhD, Jennifer Cleary, MS, Elena Frank, PhD,
Zhuo Zhao, MS, Walter Dempsey, PhD, Srijan Sen, MD, PhD
Annals of Internal Medicine. 2021; doi:10.7326/M21-1594 Published: November 16, 2021
Experiences of Work-Family Conflict and Mental Health Symptoms by Gender Among Physician Parents During the COVID-19 Pandemic
Elena Frank, PhD; Zhuo Zhao, MS; Yu Fang, MSE; Lisa S. Rotenstein, MD, MBA; Srijan Sen, MD, PhD; Constance Guille,MD
JAMA Network Open. 2021;4(11):e2134315. doi:10.1001/jamanetworkopen.2021.34315 Published: November 12, 2021
A Method for Characterizing Daily Physiology from Widely Used Wearables
Clark Bowman, Yitong Huang, Olivia J. Walch, Yu Fang, Elena Frank, Jonathan Tyler, Caleb Mayer,
Christopher Stockbridge, Cathy Goldstein, Srijan Sen, Daniel B. Forger
Cell Reports Methods, DOI:https://doi.org/10.1016/j.crmeth.2021.100058, Published: July 29, 2021
Genomic heterogeneity affects the response to Daylight Saving Time
Jonathan Tyler, Yu Fang, Cathy Goldstein, Daniel Forger, Srijan Sen & Margit Burmeister
Scientific Reports | (2021) 11:14792 |https://doi.org/10.1038/s41598-021-94459-z |Published: 20 July 2021
Genetic Interactions with Stressful Environments in Depression and Addiction
Margit Burmeister & Srijan Sen
BJPsych Advances , Volume 27 , Special Issue 3: Stress and Resilience , May 2021 , pp. 153 - 157
doi: https://doi.org/10.1192/bja.2021.21 Published: 8 June 2021
Identifying Mobile Sensing Indicators of Stress-Resilience
DA Adler, VWS Tseng, G Qi, J Scarpa, S Sen, T Choudhury
Proc. ACM Interact. Mob. Wearable Ubiquitous Technol., Vol. 5, No. 2, Article 51. Published: June 2021
Exposure to Workplace Trauma and Posttraumatic Stress Disorder Among Intern Physicians
Mary C. Vance, MD, MSc; Holly B. Herberman Mash, PhD; Robert J. Ursano, MD; Zhuo Zhao, MA, MS; Jessica T. Miller, BS;
Michael Jeremy D. Clarion, BS; James C. West, MD; Joshua C. Morganstein, MD; Abeer Iqbal, BA; Srijan Sen, MD, PhD
JAMA Network Open. 2021;4(6):e2112837. doi:10.1001/jamanetworkopen.2021.12837 Published: 8 June 2021
Differences in Gender Representation in the Altmetric Top 100
LS Rotenstein, M Torre, JL Cleary, S Sen, C Guille, DA Mata
Journal of General Internal Medicine. 1-3. doi: 10.1007/s11606-021-06829-y Published: 4 May 2021
Learning From Others Without Sacrificing Privacy: Simulation Comparing Centralized and Federated Machine Learning
Jessica Chia Liu , MA; Jack Goetz , PhD; Srijan Sen , MD, PhD; Ambuj Tewari , PhD
JMIR Mhealth Uhealth 2021; 9(3):e23728 doi: 10.2196/23728
Day-to-day Variability in Sleep Parameters and Depression Risk: a Prospective Cohort Study of Training Physicians
Yu Fang, Daniel B. Forger, Elena Frank, Srijan Sen and Cathy Goldstein
npj Digital Medicine, volume 4, Article number: 28 (2021) Published: 18 February 2021
Assessment of Disclosure of Psychological Disability Among US Medical Students
Lisa M. Meeks, PhD; Melissa Plegue, MA; Ben Case, MPH; Bonnielin K. Swenor, PhD, MPH; Srjan Sen, MD, PhD
JAMA Network Open. 2020;3(7):e2011165.doi:10.1001/jamanetworkopen.2020.11165 Published: 23 July 2020
Mental Health of Young Physicians in China During the Novel Coronavirus Disease 2019 Outbreak
Weidong Li, MD, PhD; Elena Frank, PhD; Zhuo Zhao, MS; Lihong Chen, PhD; Zhen Wang, MD; Margit Burmeister, PhD;
JAMA Network Open. 2020; 3(6):e2010705. | DOI:10.1001/jamanetworkopen.2020.10705 Published: 01 June 2020
Assessing Real-Time Moderation for Developing Adaptive Mobile Health Interventions for Medical Interns:
Timothy NeCamp, PhD, Srijan Sen, MD, PhD, Elena Frank, PhD, Maureen A. Walton, MPH, PhD, Edward L. Ionides, PhD,
Yu Fang, MSE, Ambuj Tewari, PhD, Zhenke Wu, PhD
J Med Internet Res 2020 | vol. 22 | iss. 3 | e15033, DOI: 10.2196/15033 Published online: 31 March 2020
Substantial Overlap Between Factors Predicting Symptoms of Depression and Burnout Among Medical Interns
Lisa S. Rotenstein, MD, MBA, Zhuo Zhao, MA, MS, Douglas A. Mata, MD, MPH, Constance Guille, MD, MSCR,
J Gen Intern Med, DOI: 10.1007/s11606-020-05664-x Published online: 05 February 2020
Political Events and Mood Among Young Physicians: a Prospective Cohort Study
Elena Frank, Brahmajee K Nallamothu, Zhuo Zhao, Srijan Sen
BMJ 2019;367:l6322 | doi: 10.1136/bmj.l6322 Published: 09 December 2019
Racial and Ethnic Diversity and Depression in Residency Programs: a Prospective Cohort Study
Jad A. Elharake, BS, Elena Frank, PhD, David A. Kalmbach, PhD, Douglas A. Mata, MD, MPH, and Srijan Sen, MD, PhD
J Gen Intern Med. DOI: 10.1007/s11606-019-05570-x. Published online: 03 December 2019
Association Between Physician Depressive Symptoms and Medical Errors - A Systematic Review and Meta-analysis
Karina Pereira-Lima, PhD; Douglas A. Mata, MD, MPH; Sonia R. Loureiro, PhD; José A. Crippa, MD, PhD;
Lívia M. Bolsoni, MSc; Srijan Sen, MD, PhD
JAMA Network Open. 2019; 2(11):e1916097.doi:10.1001/jamanetworkopen. 2019.16097
Change in Prevalence of Disabilities and Accommodation Practices Among US Medical Schools
Lisa M. Meeks, PhD; Ben Case, MPH; Kurt Herzer, MD, PhD, MSc; Melissa Plegue, MA; Bonnielin K. Swenor, PhD, MPH
JAMA. 2019;322(20):2022-2024. | doi: 10.1001/jama.2019.15372 Published: 26 November 2019
Genomic Prediction of Depression Risk and Resilience under Stress
Yu Fang , Laura Scott , Peter Song , Margit Burmeister and Srijan Sen
Nature Human Behaviour, Published: 28 October 2019
Gender Disparities in Work and Parental Status Among Early Career Physicians
Elena Frank, PhD; Zhuo Zhao, MS; Srijan Sen, MD, PhD; Constance Guille, MD
JAMA Network Open. 2019; 2(8):e198340.doi:10.1001/jamanetworkopen. 2019.8340. August 2, 2019
Physician Training Stress and Accelerated Cellular Aging
Kathryn K. Ridout, M.D., Ph.D., Samuel J. Ridout, M.D., Ph.D., Constance Guille, M.D., Douglas A. Mata, M.D., M.P.H.,
Huda Akil, Ph.D., Srijan Sen, M.D., Ph.D.
Biological Psychiatry (2019), doi: https:// doi.org/10.1016/j.biopsych.2019.04.030.
Altitude and Risk of Depression and Anxiety: Findings From the Intern Health Study
Brent M. Kious, Amanda Bakian, Joan Zhao, Brian Mickey, Constance Guille, Perry Renshaw, Srijan Sen
International Review of Psychiatry, DOI: 10.1080/09540261.2019.1586324
Insomnia Symptoms and Short Sleep Predict Anxiety and Worry in Response to Stress Exposure
David A Kalmbach PhD, James L Abelson MD PhD, J Todd Arnedt PhD, Zhuo Zhao MS, Jessica R Schubert PhD,
Sleep Medicine: December 5, 2018. https://doi.org/10.1016/j.sleep.2018.12.001
Residency Program Factors Associated with Depressive Symptoms in Internal Medicine Interns
Pereira-Lima, Karina, MSc; Gupta, Rahael R., MS; Guille, Constance, MD, PhD; Sen, Srijan, MD, PhD
Academic Medicine: December 18, 2018
Prevalence of Burnout Among Physicians - A Systematic Review
Lisa S. Rotenstein, MD, MBA; Matthew Torre, MD; Marco A. Ramos, MD, PhD; Rachael C. Rosales, MD;
Constance Guille,MD, MSCR; Srijan Sen, MD, PhD; Douglas A. Mata, MD, MPH
JAMA. 2018;320(11):1131-1150. doi:10.1001/jama.2018.12777
Measuring Our Values—Redoubling On A Commitment To Physician Health
Lisa S. Rotenstein; Douglas A. Mata
HEALTH AFFAIRS BLOG, AUGUST 2, 2018
JAMA February 13, 2018 Volume 319, Number 6
Chronic stress, hair cortisol and depression: A prospective and longitudinal study of medical internship
Stefanie E. Mayer, Nestor L. Lopez-Duran, Srijan Sen, James L. Abelson
Psychoneuroendocrinology, Volume 92, Pages 57–65, June 2018
Effects of Sleep, Physical Activity, and Shift Work on Daily Mood
David A. Kalmbach, Yu Fang, J. Todd Arnedt, Amy L. Cochran, Patricia J. Deldin, Adam I. Kaplin, Srijan Sen
Journal of General Internal Medicine. 14 March, 2018
The Cost of Depression-Related Presenteeism in Resident Physicians
Tracey Rosen; Kara Zivin; Daniel Eisenberg; Constance Guille; Srijan Sen
Academic Psychiatry 2017
Work-Family Conflict and the Sex Difference in Depression Among Training Physicians
Constance Guille, MD; Elena Frank, PhD; Zhuo Zhao, MS; David A. Kalmbach, PhD; Paul J. Nietert, PhD;
Douglas A. Mata, MD, MPH; Srijan Sen, MD, PhD
JAMA Internal Medicine, Published online October 30, 2017.
Sleep Disturbance and Short Sleep as Risk Factors for Depression and Perceived Medical Errors in First-Year Residents
David A. Kalmbach, PhD; J. Todd Arnedt, PhD; Peter X. Song, PhD; Constance Guille, MD; Srijan Sen, MD, PhD
SLEEP, Vol. 40, No. 3, 2017
Prevalence of Depression, Depressive Symptoms, and Suicidal Ideation Among Medical Students
A Systematic Review and Meta-Analysis
Lisa S. Rotenstein, BA; Marco A. Ramos, MPhil; Matthew Torre, MD; J. Bradley Segal, BA, BS; Michael J. Peluso,MD, MPhil;
Segal, BA, BS; Michael J. Peluso,MD, MPhil; Constance Guille,MD, MS; Srijan Sen, MD, PhD; Douglas A. Mata, MD, MPH
JAMA. 2016;316(21):2214-2236. doi:10.1001/jama.2016.17324
Healing Medicine’s Future: Prioritizing Physician Trainee Mental Health
Kathryn Baker, MD, and Srijan Sen, MD, PhD
AMA Journal of Ethics® / June 2016, Volume 18, Number 6: 604-613
In Their Own Words: An Analysis of the Experiences of Medical Interns Participating in a Prospective Cohort Study of Depression
Douglas A. Mata, MD, MPH, Marco A. Ramos, MPhil, MSEd, Michelle M. Kim, MD, PhD,
Constance Guille, MD, MS, and Srijan Sen, MD, PhD
Academic Medicine / 2016
Prevalence of Depression and Depressive Symptoms Among Resident Physicians
Douglas A. Mata, MD, MPH; Marco A. Ramos, MPhil, MSEd; Narinder Bansal, PhD; Rida Khan, BS;
Constance Guille,MD, MS; Emanuele Di Angelantonio,MD, PhD; Srijan Sen, MD, PhD
JAMA. 2015;314(22):2373-2383. doi:10.1001/jama.2015.15845
Web-Based Cognitive Behavioral Therapy Intervention for the Prevention of Suicidal Ideation in Medical Interns
Constance Guille, MD; Zhuo Zhao, MS; John Krystal, MD; Breck Nichols, MD; Kathleen Brady,MD, PhD; Srijan Sen, MD, PhD
JAMA Psychiatry. doi:10.1001/jamapsychiatry.2015.1880 Published online November 4, 2015.
Institution and Specialty Contribute to Resident Satisfaction With Their Learning Environment and Workload
Larry D. Gruppen, PhD, R. Brent Stansfield, PhD, Zhuo Zhao, MS, and Srijan Sen, MD, PhD
Academic Medicine, Vol. 90, No. 11 / November Supplement 2015
The development of depressive symptoms during medical internship stress predicts worsening vascular function
Jess G. Fiedorowicz, Vicki L. Ellingrod, Mariana J. Kaplan, Srijan Sen
Journal of Psychosomatic Research, PSR-09034; No of Pages 3. 2015
The differential influence of life stress on individual symptoms of depression
Fried EI, Nesse RM, Guille C, Sen S.
Acta Psychiatrica Scandinavica, 2015: 1–7
Appropriate approaches to summarizing GxE studies
Amy L. Byrd MS, Aidan G.C. Wright PhD, Srijan Sen MD, PhD, Kerby Shedden PhD, Stephen B. Manuck PhD
Biological Psychiatry, http://dx.doi.org/10.1016/j.biopsych. 2014.02.009
Work Compression in the Era of Duty Hour Restrictions
Dr. Srijan Sen, M.D., Ph.D., Dr. Breck Nichols, M.D., M.P.H., and Dr. Aashish K. Didwania, M.D.
JAMA Intern Med. 173(19): 1844–1845. 2013 October 28.
Effects of the 2011 Duty Hour Reforms on Interns and Their Patients A Prospective Longitudinal Cohort Study
S Sen, HR Kranzler, AK Didwania, AC Schwartz, S Amarnath, JC Kolars, GW …
JAMA Internal Medicine 173 (8), 657-662. 2013. April 22.
Depression is more than the sum score of its parts: individual DSM symptoms have different risk factors
EI Fried, RM Nesse, K Zivin, C Guille, S Sen.
Psychological Medicine, 1-10. 2013.
Well-Being and the Risk of Depression under Stress
F Grant, C Guille, S Sen.
PloS one 8 (7), e67395. 2013.
Trajectories of depressive symptoms in response to prolonged stress in medical interns
C Guille, S Clark, AB Amstadter, S Sen.
Acta Psychiatrica Scandinavica. 2013.
Gene× Environment Interaction Models in Psychiatric Genetics
K Karg, S Sen.
Behavioral Neurogenetics, 441-462. 2012.
Prescription drug use and self-prescription among training physicians
C Guille, S Sen.
Archives of internal medicine 172 (4). 371, 2012.
Reporting bias in industry-supported medication trials presented at the American Psychiatric Association meeting
S Sen, M Prabhu.
Journal of Clinical Psychopharmacology 32 (3), 435. 2012.
Socioeconomic status and mental health: what is the causal relationship?
Acta Psychiatrica Scandinavica 125 (3), 187-188. 2012.
The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation
K Karg, M Burmeister, K Shedden, S Sen.
Archives of General Psychiatry 68 (5), 444. 2011.
A prospective cohort study investigating factors associated with depression during medical internship
S Sen, HR Kranzler, JH Krystal, H Speller, G Chan, J Gelernter, C Guille.
Archives of General Psychiatry 67 (6), 557. 2010.
Utilization and barriers to mental health services among depressed medical interns: a prospective multisite study
C Guille, H Speller, R Laff, CN Epperson, S Sen.
Journal of Graduate Medical Education 2 (2), 210-214. 2010.